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Treating animals with amiodarone and grapefruit juice (27 ml/kg b.w.) caused an improvement in histological and histochemical appearance of the kidney together with decrease of serum creatinine and blood urea nitrogen. Besides, animals administered with amiodarone showed an increase of apoptotic bands as detected by gel electrophoresis. Talk with your healthcare provider if you have any of these side effects. Combining grapefruit with your statin medication can cause a higher chance of more severe side effects like muscle pain, joint pain, or even rhabdomyolysis. Histochemical examination of the renal tubules revealed depletion of glycogen and total proteins. Other statins, like rosuvastatin, pravastatin, and pitavastatin, do not have this interaction. Created for people with ongoing healthcare needs but benefits everyone. There is no interaction between lisinopril and zoloft with tart cherry juice by my knowledge except its daily use for months may lower systolic pressu. Amiodarone caused marked elevation in serum creatinine and blood urea nitrogen. Nephrology and Dialysis 44 years experience. Administration of amiodarone by gastric intubation (18 mg/kg body weight (b.w.), daily for 5 weeks) caused many histological alterations including intertubular leucocytic infiltrations, degeneration of the renal tubules, and atrophy of the glomeruli. The present work studied the effect of amiodarone on the kidney of albino rats and the possible ameliorative role of grapefruit juice. However, there does not appear to be research on the effects of zinc supplementation in people taking these drugs, so consult your physician before taking zinc supplements.Amiodarone is a potent antiarrhythmic drug that is used to treat ventricular and supraventricular tachyarrhythmias. To be safe, it's best to take iron supplements and ACE inhibitors at different times of the day.īe aware that lisinopril and other ACE inhibitors may deplete zinc levels in the body and increase the risk of zinc deficiency ( Golik, J Am Coll Nutr 1998 Trasbare, J Trace Elem Med Biol 2007). Jack Rubin answered Nephrology and Dialysis 50 years experience Lisinopril and juice: Lisinopril is not known to have any interaction with grapefruit juice. (The herb Dong Quai may also increase sun sensitivity, and potentially have a similar effect ( National Toxicology Program 2008).Īlthough there is some preliminary evidence that iron supplements may help to alleviate dry cough caused by ACE inhibitors, iron may interfere with the absorption of ACE inhibitors (and likewise, these drugs may inhibit the absorption of iron). Does eating grapefruit interfere with lisinopril Dr.

Lisinopril can increase blood potassium levels. John's wort while taking an ACE inhibitor could increase this effect. A: Lisinopril food interactions consist of foods high in potassium. John's Wort may increase sensitivity to the sun (photosensitivity), as can lisinopril and other ACE inhibitors ( Lisinopril Prescribing Information 2008 Friedman, Arch Intern Med 2012). Use arginine cautiously if taking lisinopril. Licorice supplements and other licorice products that have had glycyrrhizin removed, known as deglycyrrhizinated licorice (DGL), are available and may not have the same adverse effects as licorice containing glycyrrhizin ( Omar, Ther Adv Endocrinol Metab 20).Īrginine may cause a mild reduction in blood pressure, although not all studies have shown a consistent effect ( Komers, J Hypertens 2000 Zoja, Kidney Int 2003). Licorice contains glycyrrhizin, a compound that can increase sodium retention and blood pressure ( Deutch, Foods 2019). (Be aware that coconut water can contain high amounts of potassium). Do not take potassium without medical supervision. Taking potassium supplements with these medications could potentially increase the risk of dangerously high blood levels of potassium, a condition called hyperkalemia. Potassium supplements should be avoided by people taking lisinopril (Zestril, Prinivil) ramipril (Altace) or other ACE inhibitors that can increase potassium levels. There are no supplements that you should necessarily take because you are on an ACE inhibitor. Yes, if you take lisinopril (Zestril, Prinivil) or another ACE inhibitor such as enalapril (Vasotec), quinapril (Accupril), benazepril (Lotensin), or ramipril (Altace) for high blood pressure or congestive heart failure, certain supplements may cause problems and a particular mineral supplement should be taken at a different time of day than your ACE inhibitor.